Impact of Some Antioxidants (Allicin-AL, Saponin -SN, Carotenes-CN, Euginol, Vitamins C and E) Rich Vegetables on Common Metabolic Lipid Parameters
Uhiara Ngozi Sunday,
Ohanwe Cyprian Nnanwa,
Clement Ezeaku Anikezie,
Adesanya Oluwatosin Dorothy,
Samuel Emmanuel,
Jacob Gabriel Anayo,
Uhiara Nkolika Leontina,
Yelmi Bitrus
Issue:
Volume 9, Issue 2, April 2023
Pages:
18-21
Received:
3 February 2023
Accepted:
4 March 2023
Published:
11 April 2023
Abstract: Attempt at comparing the impact of some antioxidant – rich vegetables (singularly or combinations) on common atherosclerosis lipid parameters. The experiments were conducted in three phases. Phase (A) Five (5) ml each of aqueous extract of (i) fresh (ocimum gratissimum) scent leaf (ii) bitter leafs (vernonia amygdalina) (iii) 2.5ml each of bitter leaf and scent leaf mix; was mixed thoroughly with 100g of normal rat feed. Phase (B) five (5) ml each of aqueous extract of (i) utazi (gongronema latifolium) leafs (ii) aloevera leafs (iii) 2.5g each of utazi and aloe vera mix; was mixed into 100g normal rat feed. The third phase involved 5g each of (i) fresh (docasus carota) carrot (ii) tomato (solanum lycopersicum) (iii) carrot and tomato mix. Each of the nine (9) feed samples (3 from each phase) were separately feed to a set of three albino rats for 21 days; so was 100% (control) rat feed and garlic supplemented (5g crushed garlic, blended with 100g) rat feed. The weights, feed intake and weight of droppings of the rats were recorded at three days’ intervals during experimental feeding. The blood samples of the rats were harvested at the end of the 21 days and lipid analysis carried out on them. The rat feeds supplemented with utazi, nchanwu and aloevera leafs’ water extracts respectively scored 2.7, 3.7 and 2.9mmol/ml respectively regarding total cholesterol; all significantly lower than the normal range of 5.17mmol/ml (p ≤ 0.05). With respect to triglycerides, 1.9, 1.9 and 1.7 respectively scored by Utazi, aloe vera and bitter leaf supplemented feeds were all close to the acceptable range of 0.7 – 1.7Mmol/ml. The combined effect of utazi and Aloe vera on HDL, was significantly lowering (0.5Mmol/ml) compared to 1.5 and 1.6 Mmol/ml of individual Utazi and Aloe vera respectively. The three feed samples (Utazi/aleovera, tomatoe/carrot and bitter leaf/scent leaf) that combined two vegetables rich in same or different antioxidants, all reported lower weight gains with collaborating lower scores in lipid parameters; clue for broad spectrum anti atherosclerosis therapy preparation.
Abstract: Attempt at comparing the impact of some antioxidant – rich vegetables (singularly or combinations) on common atherosclerosis lipid parameters. The experiments were conducted in three phases. Phase (A) Five (5) ml each of aqueous extract of (i) fresh (ocimum gratissimum) scent leaf (ii) bitter leafs (vernonia amygdalina) (iii) 2.5ml each of bitter l...
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Discontinuation Patterns Among Women Using Jadelle Contraceptive Devices in a Tertiary Hospital in South-South Nigeria
Obinna Njoku,
Matthias Gabriel Abah,
Uduak Solomon Ocheche,
Emmanuel Columba Inyangetoh,
Mbereobong Saturday Etuk
Issue:
Volume 9, Issue 2, April 2023
Pages:
22-27
Received:
18 March 2023
Accepted:
10 April 2023
Published:
22 May 2023
Abstract: Introduction: The Jadelle subdermal contraceptive implant is a widely used hormonal contraceptive consisting of two rods, each consisting of a Levonorgestrel-releasing core encased in thin-walled silicon-rubber tubing. Our study examined the prevalence and discontinuation patterns of Jadelle among women in a Southern Nigerian Hospital. Materials and Methods: A review of the discontinuation patterns among Jadelle contraceptive device users in the University of Uyo Teaching Hospital over 3 years was carried out. The Case files of all clients who used Jadelle implant over the period were retrieved and analyzed. Results: Out of 2,980 clients using different contraceptive methods during the study period, 231 clients (7.8%) used the Jadelle implant. Of the 198 (85.7%) case notes available, most (52%) of them were aged 30-34 years, had attained a tertiary level of education (50.4%), and were grand-multiparous (50%). Fifty-six (56.6%) percent of clients used Jadelle for birth spacing while 44.5% used it for limiting family sizes. The most common menstrual pattern at 24 months follow-up was Amenorrhea (50%). Sixty clients (30.3%) discontinued the method for reasons which include the desire for pregnancy (48.3%), side effects (25%), change of method (11.5%), and husbands` view (5%). Discontinuation was more among the younger clients less than 36 years (86.7%). Conclusion: The Jadelle contraceptive device is associated with a number of side effects, however, the major reason for discontinuation was the desire for pregnancy, followed by the complications arising from Jadelle use. There is a need for more detailed client and spousal counseling, especially on the side effects of Jadelle to reduce discontinuation due to them.
Abstract: Introduction: The Jadelle subdermal contraceptive implant is a widely used hormonal contraceptive consisting of two rods, each consisting of a Levonorgestrel-releasing core encased in thin-walled silicon-rubber tubing. Our study examined the prevalence and discontinuation patterns of Jadelle among women in a Southern Nigerian Hospital. Materials an...
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